Evidence Based Hair
Evidence based hair is a weekly podcast hosted by Dr Jeff Donovan, a Canadian dermatologist and hair specialist. Each week, Dr. Donovan highlights recently published hair loss research from around the world.
Episodes
Monday Apr 04, 2022
Season 1, Episode 9 (Alopecia Areata and Androgenetic Alopecia)
Monday Apr 04, 2022
Monday Apr 04, 2022
STUDIES HIGHLIGHTED
ALOPECIA AREATA
King B et al (starts at 3:27). Two Phase 3 Trials of Baricitinib for Alopecia Areata. N Engl J Med. 2022 Mar 26.
Fenentinos P et al (starts at 16:24). Assessing the role of stressful life events in the induction and recurrence of alopecia areata: a case-control study. J Am Acad Dermatol. 2022 Mar 24;S0190-9622(22)00526-6.
Macbeth A et al (starts at 21:14). The associated burden of mental health conditions in alopecia areata: A population-based study in UK primary care. Br J Dermatol. 2022 Feb 14.
Senna M et al (starts at 29:06). Predictors of Quality of Life in Patients with Alopecia Areata. J Invest Dermatol 2022 Mar 21;S0022-202X
ANDROGENETIC ALOPECIA
Ghafoor R et al (starts at 39:15). Association of androgenetic alopecia and severity of coronavirus disease 2019. J Cosmet Dermatol. 2022 Mar;21(3):874-879.
Baghani M et al (starts at 40:57). Androgenetic alopecia and COVID-19: Is there a clinical connection? J Cosmet Dermatol . 2022 Feb;21(2):420-425.
Veskovic D et al (starts at 42:04). Association of androgenetic alopecia with a more severe form of COVID-19 infection. Ir J Med Sci. 2022 Mar 23;1-6.
Monday Mar 28, 2022
Monday Mar 28, 2022
Recording of the Evidence Based Hair Podcast for the March 28, 2022 issue.
STUDIES HIGHLIGHTED
Trueb RM et al (starts at 3:27). Minoxidil-induced hypertrichosis in a breastfed infant. J Eur Acad Dermatol Venereol. 2022 Mar;36(3):e224-e225.
Gangal et al (starts at 7:08). Mask-associated acquired trichorrhexis nodosa of the beard. JAAD Case Rep. 2022 Mar;21:101-102.
Trueb RM et al. Prepubertal pattern hair loss (starts at 13:38) Clin Exp Dermatol. 2022 Jan;47(1):173-175.):24-30
Katayama S et al (starts at 17:00). Rapidly Progressive Hair Loss May Be the Only Sign of Syphilis. Am J Med 2022 Feb 22;S0002-9343(22)00130-9.
Kolla et al (starts at 32:34). Dermatologists' knowledge of dermoscopic features in hair and nail disorders. J Eur Acad Dermatol Venereol. 2022 Feb 11.
Rutnin S et al (starts at 37:32)). Variation of Hair Follicle Counts among Different Scalp Areas: A Quantitative Histopathological Study. Skin Appendage Disord. 2022 Jan;8(1):24-30.
Xie et al (starts at 42:27). Hair shaft miniaturization causes stem cell depletion through mechanosensory signals mediated by a Piezo1-calcium-TNF-α axis. Cell Stem Cell 2022 Jan 6;29):
Monday Mar 21, 2022
Season 1, Episode 7 (Scarring Alopecia)
Monday Mar 21, 2022
Monday Mar 21, 2022
STUDIES HIGHLIGHTED
FFA STUDIES
Dubin C et al (starts at 2:50). Scalp and serum profiling of frontal fibrosing alopecia reveals scalp immune and fibrosis dysregulation with no systemic involvement. J Am Acad Dermatol. 2022 Mar;86(3):551-562. doi: 10.1016/j.jaad.2021.05.016
Starace et al (starts at 12:31). Clinical and Dermoscopic Approaches to Diagnosis of Frontal Fibrosing Alopecia: Results From a Multicenter Study of the International Dermoscopy Society. Dermatol Pract Concept. 2022 Jan 1;12(1):e2022080
Rayinda T et al (starts at 17:25). Clinical characteristics of male frontal fibrosing alopecia: a single-centre case series from London, UK. Br J Dermatol. 2022 Jan;186:195-197
LPP STUDIES
Moussa A et al (starts at 21:51). Treatment of lichen planopilaris with baricitinib: A retrospective study. J Am Acad Dermatol. 2022 Feb 21;S0190-9622(22)00338-3
Mostafa N et al (starts at 25:24). Mycophenolate mofetil and lichen planopilaris: systematic review and meta-analysis. J Dermatolog Treat . 2022 Feb;33(1):369-372.
FOLLICULITIS DECALVANS STUDIES
Iorizzo M et al (starts at 27:25). Refractory folliculitis decalvans treated with adalimumab: a case series of 23 patients. J Am Acad Dermatol 2022 Mar 1;S0190-9622(22)00358-9.
CCCA STUDIES
Roche FC et al (starts at 33:01). Association of type 2 diabetes with central centrifugal cicatricial alopecia: A follow-up study. J Am Acad Dermatol. 2022 Mar;86(3):661-662.
Collins MS et al (starts at 37:45). Increased risk of vitamin D deficiency and insufficiency in Black patients with central centrifugal cicatricial alopecia. J Am Acad Dermatol . 2022 Feb 15;S0190-9622(22)00272-9.
Powe et al. Vitamin D-binding protein and vitamin D status of black Americans and white Americans. N Engl J Med 2013 Nov 21;369(21):1991-2000.
Brown L et al. The vitamin D paradox in Black Americans: a systems-based approach to investigating clinical practice, research, and public health - expert panel meeting report. BMC Proc . 2018 May 9;12(Suppl 6):6.
Monday Mar 14, 2022
Monday Mar 14, 2022
STUDIES HIGHLIGHTED IN THIS EPISODE
TELOGEN EFFLUVIUM
Lytvyn et al (starts at 2:15). Comparing the frequency of isotretinoin-induced hair loss at
Monday Mar 07, 2022
Season 1, Episode 5 (Androgenetic Alopecia and Alopecia Areata)
Monday Mar 07, 2022
Monday Mar 07, 2022
STUDIES HIGHLIGHTED IN THIS EPISODE
Qui Y et al (starts at 2:41). Systematic Review and Meta-analysis of the Association Between Metabolic Syndrome and Androgenetic Alopecia. Acta Derm Venereol. 2022 Feb 8;102:adv00645
Gupta AK et al (starts at 8:38). Relative Efficacy of Minoxidil and the 5-alpha Reductase Inhibitors in Androgenetic Alopecia Treatment of Male Patients: A Network Meta-analysis. JAMA Dermatol. 2022 Feb 2:e215743
Plante J (starts at 23:13). Perifollicular inflammation and follicular spongiosis in androgenetic alopecia. J Am Acad Dermatol 2022Feb;86(2):437-438.
Qiu et al (starts at 28:04). Efficacy assessment for low-level laser therapy in the treatment of androgenetic alopecia: a real-world study on 1383 patients. Lasers Med Sci. 2022
Yale K et al (starts at 33:53). A year in review: A cross-sectional study of alopecia areata and risk of COVID-19 infection, hospitalization, and mortality from March 2020 -February 2021 Int J Dermatol. 2022 Mar;61(3):e81-e83.
Lee MM (starts at 38:10). Alopecia areata following COVID-19 vaccination: vaccine-induced autoimmunity? Int J Dermatol. 2022 Feb
Bardazzi et al (starts at 39:04). New insights on alopecia areata during COVID-19 pandemic: when infection or vaccination seems to play a role. J Cosmet Dermatol. 2022 Feb 188.
Scollan M et al (starts at 41:08). Alopecia areata after SARS-CoV-2 vaccination JAAD Case Rep. 2022 Feb;20:1-5.
Harries M et al (starts at 43:42). The epidemiology of alopecia areata: a population-based cohort study in UK primary care. Br J Dermatol. 2022 Feb;186(2):257-265.
Gutierrez Y et al (starts at 49:38). Alopecia areata in the United States: a ten-year analysis of patient characteristics, comorbidities, and treatment patterns. Dermatol Online J. 2021 Oct 15;27(10)
Monday Feb 28, 2022
Monday Feb 28, 2022
STUDIES HIGHLIGHTED IN THIS EPISODE
Korbi M et al (starts at 1:58). Topical minoxidil-induced paresthesia. Dermatol Ther. 2022 Jan 20;e15328.
Panigrahi M et al (starts at 9:37). A recent surge of doxycycline-induced pill esophagitis during the corona virus disease 2019 (COVID-19) pandemic. Indian J Gastroenterol Jan 2022
Panigrahi M et al (starts at 14:45). A recent surge of doxycycline-induced pill esophagitis during the corona virus disease 2019 (COVID-19) pandemic. Indian J Gastroenterol Jan 2022
Bommareddy et al (starts at 18:48). Association of Spironolactone Use With Risk of Cancer: A Systematic Review and Meta-analysis. JAMA Dermatol 2022 Feb 9
Ytterberg SR et al (starts at 25:13). Cardiovascular and Cancer Risk with Tofacitinib in Rheumatoid Arthritis. N Engl J Med. 2022 Jan 27;386(4):316-326. doi:
Snast I et al (starts at 37:45). Paradoxical Hypertrichosis Associated with Laser and Light Therapy for Hair Removal: A Systematic Review and Meta-analysis Am J Clin Dermatol 2021 Sep;22(5):615-624
Monday Feb 21, 2022
Season 1, Episode 3 (Scarring Alopecia)
Monday Feb 21, 2022
Monday Feb 21, 2022
STUDIES HIGHLIGHTED IN THIS EPISODE
FRONTAL FIBROSING ALOPECIA STUDIES
Maghfour J et al (starts at 3:09). The Association between Frontal Fibrosing Alopecia, Sunscreen, and Moisturizers: A Systematic Review with a Meta-Analysis. J Am Acad Dermatol. 2022 Jan 21 (online).
Sun et al (starts at 6:36). Characterization and Treatment of Prominent Facial Vasculature in the Setting of Frontal Fibrosing Alopecia J Am Acad Dermatol 2022 Jan 5; (online)
Lobato-Berezo et al (starts at 11:05). Frontal fibrosing alopecia in men: A multicenter study of 39 patients. J Am Acad Dermatol. 2022 Feb;86(2):481-484.
Bernardez C et al (starts at 13:57). Beard loss in men with frontal fibrosing alopecia. J Am Acad Dermatol. 2022 Jan;86(1):181-183.
LICHEN PLANOPILARIS STUDIES
Gardellini A et al (starts at 20:26). Lichen planopilaris-like eruption in chronic myeloid leukemia patient during treatment with nilotinib as second-line therapy. J Oncol Pharm Pract. 2022 Jan 17 (online)
Lahouel et al. Nilotinib-induced lichen planopilaris. Int J Dermatol. 2022 Jan;61(1):e37-e38.
CENTRAL CENTRIFUGAL CICATRICIAL ALOPECIA STUDIES
Jamerson et al (starts at 30:00). Gene expression profiling suggests severe, extensive central centrifugal cicatricial alopecia may be both clinically and biologically distinct from limited disease subtypes Exp Dermatol. 2022 Jan 10
FOLLICULITIS DECALVANS STUDIES
Moussa A et al (starts at 34:58). Successful treatment of folliculitis decalvans with baricitinib: A case series. Australas J Dermatol. 2022 Jan 22.
Monday Feb 14, 2022
Season 1, Episode 2 (Telogen Effluvium, Trichotillomania, Tinea Capitis)
Monday Feb 14, 2022
Monday Feb 14, 2022
STUDIES REFERENCED IN THIS EPISODE
TELOGEN EFFLUVIUM - HAIR LOSS FOLLOWING COVID 19
STUDY 1 (starts at 3:09 ): Lopez-Leon S et al. More than 50 Long-term effects of COVID-19: a systematic review and meta-analysis. medRxiv. 2021 Jan 30;2021.01.27.21250617.
STUDY 2 (starts at 4:47): Muller-Ramos P et al. Post-COVID-19 hair loss: prevalence and associated factors among 5,891 patients. Int J Dermatol 2022 Jan 26.
STUDY 3 (starts at 10:32 ): Fernandez-de-Las-Penas et al. Female Sex Is a Risk Factor Associated with Long-Term Post-COVID Related-Symptoms but Not with COVID-19 Symptoms: The LONG-COVID-EXP-CM Multicenter Study. J Clin Med. 2022 Jan 14;11(2):413.
TELOGEN EFFLUVIUM IN CHILDREN
STUDY 4 (starts at 12:45 ): Thomas et al. Single Centre Retrospective Review ofNutritional Deficiencies Associated With Telogen Effluvium in the Paediatric Population in Canada. J Cut Med Surg Jan 2022 (online)
TRICHOTILLOMANIA
STUDY 5 (starts at 18:44) : Moattari et al. Adverse psychocutaneous effects of prescription stimulant use and abuse: A systematic review. J Dtsch Dermatol Ges. 2022 Jan;20(1):7-15.
STUDY 6: (starts at 23:12); Vaccaro et al. Erosive pustular dermatosis of the scalp as local complication of trichotillomania. J Cosmet Dermatol. 2022 Jan 8. 2022 Jan 8
TINEA CAPITIS
STUDY 7 (starts at 27:51): Friedland et al. Epidemiologic features and risk of scarring in pediatric patients with kerion celsi. Pediatr Dermatol. 2022 Jan 13. doi: 10.1111/pde.14916. Online ahead of print.
Monday Feb 07, 2022
Season 1 Episode 1 (Androgenetic Alopecia and Alopecia Areata)
Monday Feb 07, 2022
Monday Feb 07, 2022
REFERENCED STUDIES FOR ANDROGENETIC ALOPECIA
Silva et al (starts at 1:10). Randomized clinical trial of low-dose oral minoxidil for the treatment of female pattern hair Loss: 0.25 mg versus 1 mg. Journal of the American Academy of Dermatology; Online Jan 2022.
Therianou et al (starts at 3;18). How Safe Is Prescribing Oral Minoxidil in Patients Allergic to Topical Minoxidil? Journal of the American Academy of Dermatology. J Am Acad Dermatol Feb 2022.
James JF et al. (starts at 4:51) Efficacy and safety profile of oral spironolactone use for androgenic alopecia: A systematic review. J Am Acad Dermatol. Feb 2022
Plante et al (starts at 8:05). The Need for Potassium Monitoring in Women on Spironolactone for Dermatologic Conditions. J Am Acad Dermatol. 2022 Jan 21 Online;S0190-9622(22)00081-0.
Özcan D (starts at 10:59). Pediatric androgenetic alopecia: a retrospective review of clinical characteristics, hormonal assays and metabolic syndrome risk factors in 23 patients An Bras Dermatol. 2022 Jan 12; online
Zong et al (starts at 14:40). Prevalence of ocular anomalies is increased in women with polycystic ovary syndrome-exploration of association with PAX6 genotype. Ophthalmic Genetics. 2022 Jan 11;1-4. Online
Deng et al (starts at 15:51). Androgen receptor mediated paracrine signaling induces regression of blood vessels in the dermal papilla in androgenetic alopecia. J Invest Dermatol. Jan 2022 online
Li K et al (starts at 18:48). Association of fibrosis in the bulge portion with hair follicle miniaturization in androgenetic alopecia. J Am Acad Dermatol 2022; Jan;86(1):213-215.
REFERENCED STUDIES FOR ALOPECIA AREATA
Di Fillipo et al (starts at 22:14). Efficacy of 308-nm excimer therapy in alopecia areata: a retrospective study with long-term follow-up Photodermatol Photoimmunol Photomed 2022 Jan 21. online.
Ting H-C et al (starts at 25:30). Association between alopecia areata and retinal diseases: A nationwide population-based cohort study. J Am Acad Dermatol 2021 Nov 1; online
Abdelkader HA et al (starts at 26:24). Histone deacetylase 1 in patients with alopecia areata and acne vulgaris: An epigenetic alteration. Australas J Dermatol. 2022 Jan 25. Online.
Friday Feb 04, 2022
Welcome to Season 1 of the Evidence Based Hair Podcast
Friday Feb 04, 2022
Friday Feb 04, 2022
Introduction to the Evidence Based Hair Podcast, a podcast highlighting the latest research in hair loss. Welcome to Season 1!